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Yonghong Liang Ph.D. I-curriculum vitae

Yonghong Liang Ph.D. I-curriculum vitae

Impumelelo enkulu

Amava oPhando

  • I-Sep. 2006-yangoku Ukusebenza kwi-Ph.D (i-Organic Chemistry)
    iiprojekthi
    1. Uphando oluthile lokusebenzisana phakathi kwe-dapivirine (TMC120) kunye ne-HIV-1 reverse transcriptase
    2. Ubungakanani bemisebenzi-ubudlelwane bomsebenzi ekufundeni i-benzyl echaziweyo i-diarylpyrimidines
    3. Ukuyila, ukuhanjiswa kunye nezifundo ze-SAR ze-α okanye i-β naphthyl i-diarylpyrimidines njenge-non-nucleoside inhibitors ye-HIV-1 reverse transcriptase
    4. Ukuyila kunye nokuhlanganiswa kwe-DABO njenge-two inhibitors ye-HIV-1 reverse transcriptase kunye ne-integrase

  • 2003-2006 Umviwa
    iiprojekthi
    1. 2-hydroxy-8H-naphthalen-4-one, 1-hydroxy-5, 4-naphthoquinone, 5-hydroxy-1, 9-anthraquione, 10-anthraquione, 7- -1-indenone, 5, 8-dihydroxy-1, 4-naphthoquinone), 4, 9-dihydroxyperylene-3, i-10-quinone kunye ne-hypocrellin A yafundwa ngeendlela zokufunda.
    2. Ukutshintshwa kwe-inermolecular proton ukudluliselwa kwimihlaba ye-5-hydroxyisoxazole-amanzi, i-DNA (RNA) base-dimer kunye ne-base-N-methylformamide yenziwe ngeendlela ze-DFT.
    I-2002-2003 Ulwalamano oluthile lwepropati-propati kwisakhiwo se-physicochemical ye-ketone kunye ne-aldehyde

Awards

Iphondo laseHunan eligqwesileyo kwi-Masterssis, i-2008

Ushicilelo

1. Liang, YH; U-Chen, I-ONIOM DFT / PM3 izibalo ekusebenzisaneni phakathi kwe-intendivivine kunye ne-HIV-1 reverse transcriptase, isifundo sobugcisa. IDrug Discov. Ther. 2007, 1, 57-60.

2. Liang, YH; I-Chen, ii-FE QSAR zifundo ze-diarylpyrimidines ngokuchasene ne-HIV-1 reverse transcriptase uhlobo olusendle kunye neentsholongwane. I-eur. J. Med. Chem. 2009, 44, 625-631

3. Liang, YH; Feng, XQ; Zeng, ZS; Chen, FE; Balzarini, J .; Pannecouque, C; De Clercq, E. Design, Synthesis, kunye ne-SAR ye-Naphthyl-Substituted Diarylpyrimidines njenge-Non-Nucleoside Inhibitors ye-HIV-1 Reverse Transcriptase. ChemMedChem 2009, 4, 1537-1545.

4. Feng, XQ; Liang, YH; Zeng, ZS; Chen, FE; Balzarini, J .; Pannecouque, C; De Clercq, E. Ulungiso lwezakhiwo ze-DAPY Analogues kunye nomsebenzi onamandla wokulwa ne-HIV-1. ChemMedChem 2009, 4, 219.

5. Zeng, ZS; Liang, YH; Feng, XQ; Chen, FE; Balzarini, J .; Pannecouque, C; De Clercq, E. Ukuphuculwa kolawulo lwe-diarylpyrimidines njenge-inhibitors ye-non-nucleoside i-HIV-1 reverse transcriptase, i-ChemMedChem 2010, yamkelwe.

6. Liang, YH; Yi, PG Ucwaningo lweengxelo malunga nesakhiwo, amandla kunye ne-intramolecular transfer proton ye-alkannin. I-Chemical Physics Lettters, 2007, 438, 173.

7. Liang, YH; Yi, PG; I-Peng, HL Uphononongo olusisiseko lwesakhiwo, amandla kunye ne-intramolecular ukudluliselwa kwe-hydrogen ye-hypocrellin A. i-Chemical Physics Letters, i-2008, i-466, i-6-10.

8. Liang, YH; Yi, PG. I-Cao, i-CZ Uphononongo olusisiseko kwi-proton yokuncediswa kwe-proton kwi-5-hydroxyisoxazole. Umbhalo we-Molecular Structure: Theochem, 2005, 729, 163-167.

9. Yi, PG .; Liang, YH; I-Cao, i-CZ Iprotamolecular proton okanye i-hydrogen-atom ukudluliselwa kumhlaba kunye namazwe ajabulisayo ye-2-hydroxybenzophenone: I-Study theory. I-Chemical Physics, 2005, 319, 297.

10. Yi, PG .; I-Liang, YH Iingcali zeengcamango zokudibanisa kunye neempembelelo ezincedisayo kwi-intramolecular proton ukudluliselwa kumazwe kunye namazwe ajabule. I-Chemical Physics, 2006, 322, 382.

11. Yi, PG .; ULiang, YH Tang, ZQ Ukufundiswa kweengxelo ze-intermolecular proton ukudlulisela impendulo kwi-5-hydroxyisoxazole-water complexes. I-Chemical Physics, 2006, 2006, 322, 387.

12. Liang, YH; Zeng, ZS; Feng, XQ; Chen, FE; Balzarini, J .; Pannecouque, C; De Clercq, E. Synthesis Synthesis kunye noVavanyo lweZibalo ze-Diarylpyrimidines kunye nomsebenzi onguNtsholongwane ka-HIV-1. Med. Chem. 2010, 18 (13), 4601.

13. Liang, YH; Zeng, ZS; Feng, XQ; Chen, FE; Balzarini, J .; Pannecouque, C; De Clercq, E. Uyilo lwe-DABO njenge-two inhibitors ye-HIV-1 reverse transcriptase kunye ne-integrase. J. Med. Chem.

14. U-Chen, u-FE, u-Liang, uYH Inkqubela yangoku kwi-Multi-target I-Anti-AIDS Iidakamizwa, i-Progess in Chemistry (8), i-Peng, i-SQ Ed, i-2011, i-167.

15. Chen, FE, Liang, YH, Zeng, ZS PCT / CN2009 / 075931.

16. Zeng, ZS, Liang, YH, Zhang, JY, Xiong, JC i-China Patent, i-CN201110070027.4

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